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A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signaling.

机译：新型小檗胺衍生物通过上调miRNa-4284和JNK / ap-1信号传导，抑制细胞活力并诱导人胶质母细胞瘤癌干细胞样细胞凋亡。

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Fan Yang; Sangkil Nam; Christine E Brown; Robin Zhao; Renate Starr; Yuelong Ma; Jun Xie; David A Horne; Linda H Malkas; Richard Jove; Robert J Hickey;
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1. A novel synthetic derivative of the natural product berbamine inhibits cell viability and induces apoptosis of human osteosarcoma cells, associatedwith activation of JNK/AP-1 signaling [J] . YangF., NamS., ZhaoR., Cancer biology & therapy . 2013,第11期

机译：天然产物贝巴明的新型合成衍生物抑制细胞活力并诱导人骨肉瘤细胞凋亡，并激活JNK / AP-1信号传导
2. Proteasome inhibitor PS-341 induces growth arrest and apoptosis of non-small cell lung cancer cells via the JNK/c-Jun/AP-1 signaling. [J] . Yang Y, Ikezoe T, Saito T, Cancer science. . 2004,第2期

机译：蛋白酶体抑制剂PS-341通过JNK / c-Jun / AP-1信号传导诱导非小细胞肺癌细胞的生长停滞和凋亡。
3. Proteasome inhibitor MG132 induces selective apoptosis in glioblastoma cells through inhibition of PI3K/Akt and NFkappaB pathways, mitochondrial dysfunction, and activation of p38-JNK1/2 signaling. [J] . Alfeu Zanotto-Filho, Elizandra Braganhol, Ana Maria Oliveira Battastini, Investigational new drugs. . 2012,第6期

机译：蛋白酶体抑制剂MG132通过抑制PI3K / Akt和NFkappaB途径，线粒体功能障碍以及激活p38-JNK1 / 2信号传导来诱导胶质母细胞瘤细胞选择性凋亡。
4. KG-135 Inhibits COX-2 Expression by Blocking the Activation of JNK and AP-1 in Phorbol Ester-Stimulated Human Breast Epithelial Cells [C] . SIN-AYE PARK, EUN-HEE KIM, HYE-KYUNG NA, Meeting on Cell Signaling World: Signal Transduction Pathways as Therapeutic Targets . 2007

机译：KG-135通过阻断由佛波酯刺激的人乳腺癌上皮细胞中的JNK和AP-1的活化来抑制COX-2的表达
5. Cannabinol Inhibits Proliferation and Induces Cell Cycle Arrest and Apoptosis in Glioblastoma, Hepatocellular Carcinoma and Breast Cancer Cells [D] . Zhong, Nuanying. 2020

机译：大麻素抑制胶质母细胞瘤，肝细胞癌和乳腺癌细胞中的增殖和诱导细胞周期停滞和凋亡
6. A Novel Berbamine Derivative Inhibits Cell Viability and Induces Apoptosis in Cancer Stem-Like Cells of Human Glioblastoma via Up-Regulation of miRNA-4284 and JNK/AP-1 Signaling [O] . Fan Yang, Sangkil Nam, Christine E. Brown, -1

机译：通过上调miRNA-4284和JNK / AP-1信号传导一种新型的草胺衍生物可抑制细胞活力并诱导人胶质母细胞瘤类似癌的细胞凋亡。
7. [6]-Gingerol induces caspase-dependent apoptosis and prevents PMA-induced proliferation in colon cancer cells by inhibiting MAPK/AP-1 signaling. [O] . E K Radhakrishnan, Smitha V Bava, Sai Shyam Narayanan, 2014

机译：[6] -Gingerol通过抑制mapK / ap-1信号传导诱导胱天蛋白酶依赖性细胞凋亡并阻止pma诱导的结肠癌细胞增殖。

A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signaling.

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